Find Counseling > Resources > Psychology Briefs > Genetics May Help Fine-Tune Antidepressant Prescription

Genetics May Help Fine-Tune Antidepressant Prescription

Scientists at the Sungkyunkwan University School of Medicine have found a genetic variation that influences how patients respond to different classes of antidepressants.

Of 241 male and female Korean patients with major late-life depression, 136 were treated with selective serotonin reuptake inhibitors (SSRIs) for six weeks while the remaining 105 received norepinephrine reuptake inhibitors (NRIs). They were also screened for variations in the genes affecting the transport of serotonin, norepinephrine, and dopamine

Researchers found that for individuals possessing the GG variation of a gene known as NET G1287A, NRIs had an 88.3 percent success rate in comparison with just 58.7 percent for SSRIs. Individuals with other variations meanwhile, showed better response to SSRIs such as fluoxetine (Prozac).

Researchers hope further investigation will help fine-tune initial prescription based on the genetic makeup of an individual.

ABSTRACT: Monoamine Transporter Gene Polymorphisms and Antidepressant Response in Koreans With Late-Life Depression

Add to:
Digg

del.icio.us

SHARE: del.icio.us del.icio.us | Digg It! digg | Add to FURL FURL | Add to Netscape Netscape | Add to Reddit reddit | Stumble! Stumble! | Add to Yahoo! My Web BETA My Web

TrackBack

TrackBack URL for this entry:
http://www.findcounseling.com/cgi-bin/mt/mt-tb.cgi/43

Post a comment

(If you haven't left a comment here before, you may need to be approved by the site owner before your comment will appear. Until then, it won't appear on the entry. Thanks for waiting.)

Category Tag Cloud



About

This page contains a single entry from Psychology Briefs, the FindCounseling.com Blog, posted on October 4, 2006 2:27 PM.

The previous post was Montessori Socially and Academically Superior to Traditional Education, Study Says.

The next post is Influx of Boomer Addicts Enter Nursing Homes.

Many more can be found on the main index page or by looking through the Psychology Research Archives.

Subscribe

Site Search

Therapist Finder





Advanced Search